diff --git a/tests/modules/nanopb/testcase.yaml b/tests/modules/nanopb/testcase.yaml
index dfe6e51004a..7c0a48a1079 100644
--- a/tests/modules/nanopb/testcase.yaml
+++ b/tests/modules/nanopb/testcase.yaml
@@ -7,3 +7,4 @@ tests:
     integration_platforms:
       - native_sim
       - native_sim/native/64
+      - qemu_malta/qemu_malta/be # Test on Big Endian platform