diff --git a/modules/trusted-firmware-m/CMakeLists.txt b/modules/trusted-firmware-m/CMakeLists.txt
index fff2be36070..05553a31992 100644
--- a/modules/trusted-firmware-m/CMakeLists.txt
+++ b/modules/trusted-firmware-m/CMakeLists.txt
@@ -210,10 +210,6 @@ if (CONFIG_BUILD_WITH_TFM)
     set(TFM_TOOLCHAIN_FILE "toolchain_GNUARM.cmake")
     set(TFM_TOOLCHAIN_PREFIX "arm-none-eabi")
     set(TFM_TOOLCHAIN_PATH ${GNUARMEMB_TOOLCHAIN_PATH}/bin)
-  elseif(${ZEPHYR_TOOLCHAIN_VARIANT} STREQUAL "xtools")
-    set(TFM_TOOLCHAIN_FILE "toolchain_GNUARM.cmake")
-    set(TFM_TOOLCHAIN_PREFIX "arm-zephyr-eabi")
-    set(TFM_TOOLCHAIN_PATH ${XTOOLS_TOOLCHAIN_PATH}/arm-zephyr-eabi/bin)
   else()
     message(FATAL_ERROR "Unsupported ZEPHYR_TOOLCHAIN_VARIANT: ${ZEPHYR_TOOLCHAIN_VARIANT}")
   endif()